Neymar limped off after only 12 minutes of Brazils 1-1 draw having an thigh injury with Nigeria on Sunday.
As he headed down the tunnel, Philippe Coutinho replaced the 27-year-old however gave the crowd a thumbs-up.
Neymar made his appearance having attained his centenary against Senegal.
The PSG could have been expecting to beat Ronaldos record of 62 aims for Brazil, which he is one strike .
Neymar overlooked the Copa America that summer and has been plagued by injury.
A foot injury ruled him out for several months ahead of the World Cup, even though he managed to play in the championship for Brazil.
Nigeria took the lead at the 35th minute when grab his second goal in two global looks and Joe Aribo discovered space in a crowded penalty box to rifle in a very low shot in Singapore.
When Casemiro fired home from close range after he was quickest to respond when a Marquinhos header came back off the woodwork brazil equalised three minutes.
Casemiro later smacked off a header away from the pub and Coutinho should have scored a cut back with five minutes remaining but the score remained at 1-1.
Brazils winless run to four matches is extended by the draw.
Brazil dropped to Peru and Also Have attracted with Colombia and Senegal since lifting the Copa America in July.
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